Projects

Currently running projects that we coordinate or participate in

(Descriptions specify the role of VL in the project)

2021–(2024): Co-investigator of project Internal Grant Institute of Ministry of Health of CR NU21-03-00506: Tumor cell and mutational landscape in colorectal cancer development

2021–(2024): Co-investigator of project Internal Grant Institute of Ministry of Health of CR NU21-03-00145: Telomere homeostasis as potential biomarker of risk, prognosis and progression in gynaecologic tumours

2021–(2024): Member of the team of project Czech Science Foundation 21-27902S: Telomere homeostasis from colorectal adenoma to metastatic cancer

2020–(2023): Co-investigator of project Internal Grant Institute of Ministry of Health of CR NU20J-08-00009: Prevention of intestinal anastomotic leakage and postoperative adhesions by using nanofibrous biodegradable materials

2019–(2024): Co-worker of project, Horizon 2020-WIDESPREAD – CHAPERON: ERA Chair Position for Excellent Research in Oncology

2019–(2022): Member of the Action INTERCOST - LTC19: Identifying biomarkers through translational research for prevention and stratification of colorectal cancer (TRANSCOLONCAN)

2019–(2022): Co-investigator of project, Internal Grant Institute of Ministry of Health of CR NV19-09-00237: The clinicopathological and molecular factors detected in metastases, predicting of treatment response in colon cancer patient

2019–(2022): Co-investigator of project, Internal Grant Institute of Ministry of Health of CR NV19-08-00113: Feasibility study of next generation sequencing for individualized therapy of patiens with solid tumors

2018–(2022): Member of the Action COST - CA17118: Identifying Biomarkers Through Translational Research for Prevention and Stratification of Colorectal Cancer

2018–(2022): Principal investigator of partner project, MEYS CZ.02.1.01/0.0/0.0/17_048/0007280: Application of Modern Technologies in Medicine and Industry

2018–(2023): Principal investigator of project UNCE/MED/006: Centre of clinical and experimental liver surgery

2017–(2021):Co-investigator of project, MEYS CZ.02.2.69/0.0/0.0/16_018/0002455: Further development of experimental approches on solving actual medical problems at the Charles University, Faculty of Medicine in Pilsen - accreditation of new subjects of doctoral studies

Past grants and research funding

(Descriptions specify the role of VL in the project)

2017–2020: Co-investigator of project, MEYS CZ.02.1.01/0.0/0.0/16_017/0002454: Investment support of the experimental subjects for newly accredited doctoral study programs at the Charles University, Faculty of Medicine in Pilsen

2017–2019: Principal investigator of project SVV 260392/2017: Microanatomic models of liver parenchymal perfusion and in vitro model of some mesenchymal and epithelial cells in pathologic conditions as source of information for prediction of liver regeneration capacity2016: Principal investigator of project SVV 260284/2016: Analysis of vascular changes during aging and importance of perfusion for liver regeneration.

2016–2018: Co-investigator of European project Erasmus+: MedTrain3DModsim – Novel educational materials in medical training with 3D modeling applications and simulation modalities (Virtual reality and augmented reality).

2013–2015: Principal investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NS 14329): Evaluation of changes of molecular-biologic factors and their importance in prognosis of relapsing colorectal cancer after radical surgical treatment.

2012–2015: Principal investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NS 13326): Improvement of resecability of the malignant processes using the more accurate methods for measuring parametres of the remnant liver parenchyma – computer assisted diagnostic and software modeling.

2011–2014: Co-investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NS 12025): Molecular biological and histopathological characteristics of tumor infiltrating lymphocytes as tool for prediction of risk of early recurrence of colorectal cancer

2011–2013: Principal investigator of project OPVK (2.2.) Experimental surgery – new technologies in medicine

2009–2011: Principal investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NS 10230-3/2009): Rationalization of strategy of oncological treatment of radically inoperable colorectal liver metastases.

2008–2011: Principal investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NR 9731-4): Influence of neoadjuvant biological therapy upon regeneration of liver parenchyma after surgical treatment –porcine experimental model

2006–2008: Principal investigator of Grant of Internal Grant Institute of Ministry of Health of Czech Republic (IGA MZ CR NR 8860-3): Evaluation of possibility of medical use of Interleukin 6 and Tumor necrosis factor alpha for acceleration of hypertrophy of liver parenchyma – animal model simulating conditions at patients after embolization of the right branch of portal vein